Nano Weapons Functioning on the Nano Scale

نویسندگان

  • LIAN FANG DU
  • MING CHEN
  • HANG HUI WANG
  • LI FANG JING
  • YUN HUA LI
چکیده

The nano-microcapsules drug delivery system is currently a promising method for the treatment of many types of diseases, particularly tumors. However, the drug delivery efficiency does not reach a satisfactory level to meet treatment demands. Therefore, the effectiveness of delivery needs to be improved. Based on the alterations in the structure and modification of nano-microcapsules, ultrasound-targeted microbubble destruction (UTMD), a safe physical targeted method, may increase tissue penetration and cell membrane permeability, aiding the drug-loaded nano-microcapsules ingress the interior of targeted tissues and cells. The effectiveness and exact mechanism of action of the drug-loaded nanomicrocapsules delivery system mediated by UTMD have yet to be fully elucidated. In this study, the latest advancement in UTMD-mediated drug loaded nanomicrocapsules system technology was reviewed and the hindrances of UTMDmediated drug delivery were assessed, in combination with a prospective study. The findings suggested that the drug delivery efficiency of nanomicrocapsules mediated by UTMD was distinctly improved. Thus, the UTMD-mediated drug-loaded nano-microcapsules delivery system may significantly improve the efficiency of drug delivery, which may be a promising new therapeutic method.

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تاریخ انتشار 2016